|
Indications and Dosage
Oral
Constipation Adult: 3.5 g 1-3 times daily. Mix w/ a full glass of liq. Child: ≤12 yr Each level 5-mL spoonful contains 1.75 g: Half to 1 level 5-mL spoonful bid (morning and evening) to be dissolved in water. Oral Mild to moderate hypercholesterolaemia Adult: As adjunct to lipid-lowering diet: 7.5-10 g daily. Mix w/ a full glass of liq.
|
|
Administration
Should be taken on an empty stomach. Take before meals w/ a full glass of water.
|
|
Contraindications
Pre-existing faecal impaction, intestinal obstruction, natural or drug-induced reduction of gut motility, colonic atony e.g. senile megacolon.
|
|
Special Precautions
Patient w/ swallowing difficulty. Childn.
|
|
Adverse Reactions
Abdominal distention, flatulence, GI impaction, GI obstruction, hypersensitivity reactions e.g. rhinitis, conjunctivitis, bronchospasm and anaphylaxia; cutaneous symptoms (e.g. exanthema and/or pruritus).
|
|
Overdosage
Symptoms: Abdominal discomfort and flatulence. Management: Maintain adequate fluid intake.
|
|
Drug Interactions
May delay or reduce the GI absorption of other drugs e.g. cardiac glycosides, coumarin derivatives, lithium, or vit (e.g. vit B12) and minerals (e.g. Ca, Fe, or Zn).
|
|
Action
Description:
Mechanism of Action: Ispaghula husk absorbs water in the GI tract to form a mucilaginous mass which increases faecal mass, thereby promoting peristalsis. |
|
Storage
Store below 30°C.
|
|
MIMS Class
|
|
ATC Classification
A06AC01 - ispaghula (psylla seeds) ; Belongs to the class of bulk-producing laxatives.
|
|
References
Buckingham R (ed). Ispaghula. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/04/2016 . Guardian - Psyllium Husk Powder for Suspension (Guardian). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/. Accessed 11/04/2016 . Joint Formulary Committee. Ispaghula Husk. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/04/2016 .
|
Sign Out
